PublicationsThe specialists at The Chiari Care Center have published leading articles in the field including:
Oro' JJ, Mueller DM.
Neurological Research, 33(3), 2011, p 261-271.
The paper presents an in-depth reveiw of current and historical surgical approaches to the treatment of Chiair I malformaition.
Oro', JJ., Mueller DM.
The handbook presents a comprehensive review of the evaluation and treatment of Chiari malformation and syringomyelia.
BookSurge Publishing, 2008.
Mueller DM, Oro JJ
Journal of the American Academy of Nurse Practitioners. 16(3):134-138, 2004
One of the largest studies defining the broad range of symptoms in patients with the Chiari I malformation, this research study is also the first to document an emotional component of CM-I.
- The Chiari I Malformation with and without Syringomyelia and Pregnancy: Case Studies and Review of the Literature.
Mueller DM, Oro JJ:
American Journal of Perinatology. 22(2):67-70, 2005.
This report is one of the few articles in the medical literature on the role of pregnancy in the Chiari I malformation and syringomyelia.
- Prospective analysis of self-perceived quality of life before and after posterior fossa decompression among 112 patients with Chiari malformation with or without Syringomyelia.
Mueller DM, Oro JJ:
Neurosurgical Focus. 2005 Feb 15;18(2): ECP2.
One of the largest outcome studies performed in patients who have undergone surgery for the Chiari I malformation. The study is also the only one to measures outcome using a verified quality of life outcomes measure, The Sickness Impact Profile.
Arachnoid cyst resulting in tonsillar herniation and syringomyelia in a patient with achondroplasia: a case report.
Bauer A, Mueller DM, Oro JJ:
Neurosurgical Focus. 2005 Nov 15;19(5):E14
There are several "secondary" causes of Chiari malformation including tumors and arachnoid cysts. This report describes a rare case of an arachnoid cyst causing herniation of the cerebellar tonsils in a patient with achondroplasia.
Phenotypic definition of Chiari type I malformation coupled with high-density SNP genome screen shows significant evidence for linkage to regions on chromosomes 9 and 15.
Speer MC & multiple authors including Oro JJ & Mueller DM
American Journal of Medical Genetics. 140(24): 2776-2785, 2006.
This multicenter trial directed by researchers at Duke University is one of the first studies investigating the role of genetics in the development of the Chiari I malformation.